A total of 127 genes were upregulated upon JQ1 treatment and included those with a role in translational repression (EIF4EBP2, PAIP2B), induction of apoptosis (PPP1R13B) and tumour suppression (glucocorticosteroid (GC)-responsive gene FKBP51) (Figure 3b). The gene discussed is PAIP2B; the disease is neoplasm.