Dyslipidemia, the main risk factor for CVD, is a heterogeneous metabolic disorder involving multiple etiologies; it is commonly characterized by increased triglycerides, low-density lipoprotein (LDL) cholesterol and apolipoprotein B (apo-B) levels, and reduced plasma high-density lipoprotein (HDL) cholesterol [2]. The gene discussed is APOB; the disease is metabolic disease.