PVALB and schizophrenia: The doses were selected in a range far below those required for the induction of anesthesia or acute behavioral effects but high enough to induce reproducible effects on gene expression patterns, electrophysiological measures and structural alterations paralleling those in schizophrenia: In an earlier report we were able to demonstrate working and declarative memory deficits resembling of those reported in schizophrenic patients [14] and a selective loss of parvalbumin-positive GABAergic interneurons.