Tumour sections from: vehicle, fulvestrant, NVP-AST487 and fulvestrant + NVP-AST487 treatment groups were analysed by IHC for proliferation and apoptosis, using phospho-histone 3 (pH3) and cleaved caspase-3 (CC3), respectively (Supporting Information Fig S6A). The gene discussed is PHC3; the disease is neoplasm.