Immunohistochemical staining was distinguishable to show that tumor cells of CCRCC diffusely positive for CD10, vimentin and negative for E-cadherin, CK7, CK20, while that of CDC are positive for E-cadherin, CK7, vimentin, partially CD10, and negative for CK20 [9]. The gene discussed is VIM; the disease is neoplasm.