In differentiated-type gastric carcinomas (DGCs), our recent aCGH-based lineage analyses revealed two genetic lineages: one with copy-number loss of MYC and copy-number gain of TP53 (MYC− and TP53+), a dormant pattern, and the other with the copy-number gain of MYC and/or copy-number loss of TP53 (MYC+ and/or TP53−), an aggressive pattern. This evidence concerns the gene MYC and gastric carcinoma.