Corroborating the suggested link between calcium and obesity in the context of cancer [33], we found markedly different risk estimates for oesophageal cancer when stratifying according to overweight status [e.g. HR: 1.93 (95% CI: 1.32-2.82) and 0.77 (0.44-1.35) for every SD increase of albumin-corrected calcium in normoweight and overweight individuals, respectively]. The gene discussed is ALB; the disease is Obesity.