The TLR2 expression profile of human CRC tissues revealed that high levels of TLR2 correlated with more advanced pathology grades (1, 2, 3) and lymph node metastasis (N0, N1, N2) (Figures 1C and 1D; ***p < 0.001; **p < 0.01; *p < 0.05), suggesting an association between TLR2 expression and tumour progression. This evidence concerns the gene TLR2 and neoplasm.