The expression of miR-143 was significantly lower in 4 CRC cells with high TLR2 expression levels (Figure 3B and Additional file 3: Figure S3A), especially in the poorly differentiated tumour cells SW620 and HCT116, showing that miR-143 levels are inversely correlated with the levels of TLR2 expression. The gene discussed is TLR2; the disease is neoplasm.