ACE and chronic kidney disease: ACE inhibitors and ARBs reduce proteinuria, slow progression of CKD and lower morbidity and mortality rates in patients at high CVD risk, and in patients already displaying evidence of target organ damage (TOD) such as myocardial infarction (MI), heart failure (HF), stable coronary heart disease (CHD) with or without left ventricular dysfunction (LVD), and reduce mortality and reinfarction rates in patients with LVD or HF after MI [12-32].