ERVW-1 and melanoma: It is highly probable that the biogenesis of a pathologic neuromelanin depends on a complex background that compromises the immunological control of the expression of an endogenous retroviral gene product, syncytin-1 [14], as an overexpression of this cellular component can disturb redox processes within the cell [9] and thus favour the biosynthesis of a melanoma-like neuromelanin (MLN).