The HLA-DRB1*04:01 (p=0.03; OR: 17) andHLA-DQB1*03:02 (p=0.001) alleles were significantlymore frequent in male T1D patients 1-5years old at onset than females with similar condition.HLA-DRB1*03:01 (p=0.02; OR: 0.194) andHLA-DRB1*15:01 (p=0.03) alleles were significantlyhigher in female T1D patients 6-10 and 16-20 years old at onset, respectively, than males withsimilar conditions (Table 4). The gene discussed is HLA-DRB1; the disease is type 1 diabetes mellitus.