Interestingly, Wnt7a expression is lost in majority of NSCLC cells (Winn et al., 2005), and restoration of Wnt7a expression in the same cells leads to reduced cell proliferation, reduced anchorage-independent growth, increased cell differentiation and reversal of transformed phenotype (Winn et al., 2005). This evidence concerns the gene WNT7A and non-small cell lung carcinoma.