A subset of NSCLC characteristically displays loss in Wnt7a (Winn et al., 2005), hsa-miR29b (current study) and p53 (Rom and Tchou-Wong, 2003), indicating that proper activation of Wnt7a signaling might be critical for p53 regulation and NSCLC cell proliferation. The gene discussed is TP53; the disease is non-small cell lung carcinoma.