FGF2 and retinal ischemia: We show that (i) Müller cells synthesize bFGF in both rat and human retinal tissues (Figs. 1 and 2); (ii) bFGF, which was localized to Müller cells, is virtually elevated after transient retinal ischemia-reperfusion (Fig. 2); and (iii) it is retinal glial (Müller) cells that predominantly secrete bFGF in diabetic fibrovascular membranes (Fig. 1).