A recent study investigated the multiprotective mechanisms of Chinese herbal formulas for treating hypertension from the perspective of modern science, including smoothly controlling BP, reducing blood pressure variability (BPV), protecting target organs, regulating renin-angiotensin-aldosterone system (RAAS), reversing risk factors, improving endothelial function, blocking calcium channels, improving life quality and clinical symptoms, and reversing uncontrollable factors of BP [114]. This evidence concerns the gene REN and Hypertension.