sTREM-1, APACHE II score, and SOFA score as independent variables and NT-proBNP as dependent variable, Multiple logistic regression analysis showed that serum sTREM-1 level in patients with severe sepsis was an independent risk factors to myocardial dysfunction (r = 0.619, 95%  CI:  0.842–1.550, P < 0.001), in Table 3. Here, NPPB is linked to Sepsis.