The obesity risk allele of the NEGR1 SNP associated significantly with lower fat intake (P = 3.2 × 10−5) but with higher carbohydrate (P = 3.3 × 10−5) and fiber intakes (P = 1.1 × 10−4) (Electronic Supplementary Material, Table S3). The gene discussed is NEGR1; the disease is obesity due to melanocortin 4 receptor deficiency.