BDNF and obesity due to melanocortin 4 receptor deficiency: Higher protein intake associated significantly with higher BMI in all BDNF genotype groups, but this association was significantly stronger among individuals with the obesity susceptibility allele A of BDNF rs4923461 (P = 1.0 × 10−33 and 1.1 × 10−60 among GA- and AA-genotype carriers, respectively) as compared to carriers of the GG-genotype (P = 2.7 × 10−4) (Electronic Supplementary Material, Fig. 5).