TNFSF10 and acute promyelocytic leukemia: This ncRNA plays an anti-apoptotic role in All trans RA (ATRA)-induced myeloid differentiation, protecting cells against ATRA-induced apoptosis probably through the inhibition of the TNFα-related apoptosis-inducing ligand (TRAIL) pathway [123]: in the promyelocytic leukemia cell model NB4, knockdown of HOXA-AS2 increases number of both apoptotic cells and TRAIL.