ANXA5 and systemic sclerosis: SGFW treatment significantly increased Annexin V staining of cells from 1.21 ± 0.31% to 14.87 ± 1.3% in control-MVECs and from 1.80 ± 0.36% to 32.19 ± 2.84% in SSc-MVECs (Fig. 2B, P < 0.05).