The addition of BMP2 at 200 ng/ml to cells subjected to SGFW resulted in a significant increase in control-MVECs viability (from 82 ± 5.2% to 94.8 ± 5.4%, mean ± SD, P < 0.05, Fig. 3A), but had insignificant effect on SSc-MVECs viability. Here, BMP2 is linked to systemic sclerosis.