Present findings suggest that EGF-NIR may be a suitable platform technology for visualization of EGFR at different levels of expression in human biopsies of CRC tumors, complementary to the gold standard techniques of RT-PCR for EGFR mRNA quantification [46], ex vivo hybridization [47] and EGFR immunohistochemistry [26]. This evidence concerns the gene EGFR and colorectal carcinoma.