VDR and type 2 diabetes mellitus: In support of the findings, Oh and Barrett-Connor (2002) investigating VDR gene polymorphisms in individuals with type 2 diabetes in the Rancho Bernando Cohort, observed that individuals with the mutant recessive homozygous genotype, the VDR 1544410 A > G (BsmI) polymorphism, presented significantly higher levels of HOMA-IR compared to those with heterozygous or normal homozygous genotypes [20].