The “Alarmin” IL-33 is released by injured epithelia and endothelia following hookworm infection so as to attract leukocytes to the site of inflammation[33,34]; moreover, IL-33 supports reduction and expulsion of the intestinal helminths Heligmosomoides pylorus, Trichuris muris or Nippostrongylus brasiliensis from infected mice[17,35,36]. The gene discussed is IL33; the disease is ancylostomiasis.