Concerning previous work on S. oleraceus, a treatment of diabetic rats with the whole plant infusions was shown to produce a marked amelioration of the impaired glucose tolerance at all examined periods after oral glucose loading and the lowered insulin and C-peptide levels, improvement in serum lipid profile including decrease in serum total lipid, total cholesterol, triglyceride, LDL-cholesterol and vLDL-cholesterol levels and increase in HDL-cholesterol level [31]. Here, INS is linked to Impaired glucose tolerance.