In multiple stepwise regression analysis model including age, Cys, CKD-EPI(Cys), CKD-EPI(Crea-Cys), NT-proBNP, troponin I, LVMI, and IMT, only CKD-EPI(Cys) independently influenced DPI (R2  0.67; P < 0.001) (Figure 1). Here, NPPB is linked to chronic kidney disease.