Anti-CENP-A/B antibodies were detected in 31 of the 212 samples with a higher frequency in PBC/AID (14/37; 37.9 %) than in PBC (14/93; 15.1 %; p = 0.009), BN (2/61; 3.3 %; p < 0.001), and BN/AID groups (1/21; 4.8 %; p = 0.014). The gene discussed is CENPA; the disease is primary biliary cholangitis.