Increased genes on these lists include potent pro-inflammatory chemokines that recruit myeloid and lymphoid cells to the site of infection and/or tissue injury such as Cxcl9, Cxcl10, Ccl4, and Ccl12; myeloid cell receptors associated with phagocytosis of microbes (Fcgr3, Fcgr4) and maturation of phagosomes (small GTPases Igtp, Irgm1, Gbp2, Gbp3); IRF8's hetero-dimerization partner (Irf1), and early type I interferon response (Oasl2, Ifit3). Here, CCL4 is linked to infection.