Mutations in IL17F, IL17R and DECTIN1 in patients with chronic mucocutaneous candidiasis, as well as neutralizing autoantibodies against IL-17 and IL-22 in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, directly impair IL-17 and IL-22 immunity [47], [52]–[54]. Here, IL17F is linked to Chronic mucocutaneous candidosis.