Nevertheless, to rigorously test the B cell-specificity of the Th17/IL-17/neutrophilia phenotype observed in the μMT strain in acute TB (Figures 1&2), we conducted experiments involving B cell depletion via administration of CD22-cal, an effective B cell-depleting agent [47], [48] (Figure S1A), in wild-type C57BL/6 mice. This evidence concerns the gene CD22 and tuberculosis.