CD80 and autoimmune neuropathy: Our data showed that B6/B10 alleles at Idd3 and Idd5 or Idd10/18 had a synergistic protective effect on autoimmune peripheral neuropathy since NOD-B7-2KO-Idd3/5 and NOD-B7-2KO-Idd3/10/18 females were almost completely protected from disease (Fig. 3A).