The multivariate analysis taking into account age and BMI showed that the allele C for MC4R was associated with higher risk of type 2 diabetes mellitus in women (RR = 1.5 95%CI: 1.1 – 2.2, P = 0.03), but not among men (RR = 0.9 95%CI: 0.6 – 1.7, P = 0.9). The gene discussed is MC4R; the disease is diabetes mellitus.