Although this relationship did not reach statistical significance, there was a trend towards an association between higher FGF-23 concentrations and higher LVMI (β 12.06, 95% CI 0.14 to 24.1; p = 0.05 per log10FGF-23 after adjustment for age, sex, race, diabetes, hypertension, CVD, systolic blood pressure, serum albumin, hemoglobin, phosphorus, plasma 25(OH)D and 1,25(OH)2D). The gene discussed is FGF23; the disease is diabetes mellitus.