We assessed enrichment for autoimmune disease-associated regions in all VDR binding sites overlapping with ChIP-seq peaks for other transcription factors and found the greatest enrichment for overlap with SP1 and CTCF but comparisons between VDR binding sites overlapping with transcription factor ChIP-seq peaks and those without overlap were not significant [See Additional file 9: Table S5]. The gene discussed is SP1; the disease is autoimmune disease.