GPT and cholestasis: When the diet was switched back to the normal diet after the induction of cholestasis by the administration of dietary CA for 7 days (Figure 4A), the levels of serum markers indicative of cholestasis, i.e., total bilirubin (T-Bil) and total bile acids (T-BA), and those of markers for hepatocellular injury, i.e., alanine aminotransferase (ALT) and aspartate aminotransferase (AST), rapidly declined to the normal range within 3 days (Figure 4B).