WRN and Werner syndrome: The controls were two normal primary fibroblast cultures, 82-6 and 88-1 (Oshima et al., 1995; Huang et al., 2008) as well as cultures of WRN mutant fibroblasts, Registry# MCI7885, derived from a patient with classical Werner syndrome (Oshima et al., 1995; Yu et al., 1996).