IFNA1 and Autoimmunity: One fascinating feature of SjS autoimmunity in both humans and animal models of SjS is the reported high levels of IFN, both IFN-α/β and IFN-γ (Hjelmervik et al., 2005; Gottenberg et al., 2006; Kawakami et al., 2007; Spachidou et al., 2007; Perez et al., 2009; Kimoto et al., 2011; Peck et al., 2011).