IFNA1 and Schwartz-Jampel syndrome: Alternatively, if the etiological agent does turn out to be a virus, then one cannot rule out the possibility that the source of IFN in SjS, besides pDCs, is the autonomous innate response by the glandular epithelium per se involving Ifnα5 (Peck et al., 2011; Peck and Nguyen, 2012).