As presented in our previous papers (Peck et al., 2011; Peck and Nguyen, 2012), analyses of global temporal transcriptome data collected during development of SjS-like disease in the C57BL/6.NOD-Aec1Aec2 model of primary SjS defined an IFN-signature that could be used to model molecular events and their biological processes underlying SjS. Here, IFNA1 is linked to Schwartz-Jampel syndrome.