CX3CL1 and breast cancer: Utilizing inducible fibroblast growth factor receptor 1 (FGFR1) in a murine mammary tumor cell line and its endogenous expression in the breast cancer cell line, HS578T, another laboratory has recently shown that activation of this tyrosine kinase receptor leads to CX3CL1 production by tumor cells and subsequently, enhanced macrophage recruitment to mammary cells during the early stages of tumorigenesis in vitro and in vivo (Reed et al., 2012).