MALAT1 and cancer: As an example of how our results can contribute to the structure–function annotation of ncRNAs, we annotated ECS predictions associated to the long (intergenic) ncRNA MALAT1. MALAT1 (Metastasis-Associated Lung Adenocarcinoma Transcript 1, also known as Neat2) is an ∼7 kb unspliced ncRNA involved in regulating alternative splicing and is implicated in various cancers (67–72).