The mRNAs encoding IFNβ-dependent genes, such as IRF7 (Fig. 2C), IFNα4 (Fig. 2D), and IFNα6 (Fig. 2E), as well as CXCL10 (Fig. 2F) an established marker of viral infection, were also suppressed in DEAF1−/− MEFs. The gene discussed is DEAF1; the disease is viral infectious disease.