The mRNAs encoding IFNβ-dependent genes, such as IRF7 (Fig. 2C), IFNα4 (Fig. 2D), and IFNα6 (Fig. 2E), as well as CXCL10 (Fig. 2F) an established marker of viral infection, were also suppressed in DEAF1−/− MEFs. Here, IRF7 is linked to viral infectious disease.