LIN28A and astrocytoma (excluding glioblastoma): To investigate the potential role of LIN28A in gliomas, we examined LIN28A protein by immunohistochemistry in tissue microarrays (TMA) containing human glioma and GBM samples, including 20 astrocytomas (WHO grade II), 20 anaplastic astrocytomas (WHO grade III, AA), 35 pediatric glioblastoma (WHO grade IV, pGBM) and 64 adult glioblastoma (WHO grade IV, aGBM).