Fifty-six percent of Vil-Cre;BrafLSL-V637E/+; p53LSL-R172H/+ animals at an age of 10–20 months had carcinomas, as compared to 13.8% of mice in the Vil-Cre;BrafLSL-V637E/+ cohort (p = 0.002, χ2 test). The gene discussed is VIL1; the disease is carcinoma.