CD14 and systemic sclerosis: CD14+ monocytes are increased in peripheral blood of SSc patients [6], and the molecular phenotypes and the proportions of cell types in the population are altered, with a larger proportion of type I collagen-producing monocytes [15], CXCR4+ circulating cells with monocytic and endothelial features [16], monocytic proangiogenic hematopoietic cells [17], and CD163+CD204+ cells with a profibrotic M2 phenotype [6].