PLEKHG5 and Charcot-Marie-Tooth disease: We identified novel compound heterozygous mutations, c.1988C > T (p.Thr663Met, paternal origin) and c.2458G > C (p.Gly820Arg, maternal origin) in the PLEKHG5 gene in a Korean CMT family (family ID: FC307) (Figure 1A and 1B).