As shown in the tracings in Figure 2, one hour after LPS injection (3 mg/kg), the MAP dropped significantly in both genotypes, averaging 100.3 ± 4.1 vs. 84.1 ± 2.6 mmHg for the Arap1-/- mice pre- and post-sepsis, respectively (P = 0.001), and 104.0 ± 3.0 mm vs. 93.3 ± 1.2 Hg for the wildtype mice pre- and post-sepsis, respectively (P = 0.013). This evidence concerns the gene ARAP1 and Sepsis.