GNAS and preeclampsia: Herein, to observe the effect of preeclampsia, an important risk factor for low birth weight, on DNA methylation of the fetus and to explore the potential molecular mechanisms linking preeclampsia to the increased risk of cardio-vascular diseases in late life, we analyzed the methylation levels at DMRs of IGF2 and GNAS of umbilical cord blood lymphocytes of neonates born to normal pregnancy, gestational hypertension and preeclampsia.