TNF and rheumatoid arthritis: With regard to treatment with disease-modifying antirheumatic drugs (DMARDs), 15 RA patients (83%) were taking methotrexate (MTX), 2 in combination with an antitumour necrosis factor (TNF) agent (1 infliximab, 1 adalimumab), and 1 in combination with sulfasalazine (SSZ), 1 patient was on SSZ monotherapy.