NTRK2 and ischemia: Similarly as in the cortex, the expression of 140KDa TrkB largely decreased after 1-hr ischemia and 24-hr reperfusion (39.7% of the sham level, P<0.05), while DOR activation with TAN-67 greatly reversed such a decrease (80.1% of the sham level, P<0.05 vs. MCAO alone) and DOR inhibition with naltrindole tended to worsen the MCAO-induced decrease (25.9% of the sham level).