A549 lung tumor xenografts treated with paclitaxel or sEphB4-HSA as single agents had similar rates of growth to the control tumors initially following treatment but later regressed to the baseline tumor size 7–9 days later and remained at a constant size until Day 42, resulting in tumors 75–80% smaller compared to control mice (p = 0.0004 for paclitaxel versus PBS, p = 0.0003 for sEphB4-HSA versus PBS; Figure 7A). This evidence concerns the gene ALB and neoplasm.