Other risk factors for ESRD revealed in the multivariate Cox regression analysis included diabetes, decreased eGFR, diuretic use, higher MBP, proteinuria (by dipstick or by urine protein-to-creatinine ratio (UPCR)), hyperphosphatemia, higher HbA1c, lower BMI, anemia and hypoalbuminemia (Table 4). The gene discussed is MBP; the disease is diabetes mellitus.