Interestingly, AE-SN treatment only induced LC3 A/B II accumulation but not cleavage of caspase-3in HEC-1A, HEC-1B, and KLE human endometrial cells [24], with similar results demonstrated in DLD-1 and HT-29, human colorectal carcinoma cells. This evidence concerns the gene MAP1LC3A and colorectal carcinoma.