Furthermore a recent paper reports the ability of TAR miRNA to downregulate excision repair cross-complementing rodent repair deficiency, complementation group 1 (ERCC1), and immediate early response 3 (IER3) proteins, thus blocking apoptosis in infected cells [87], so a possible function of this miRNA has been in part clarified. This evidence concerns the gene IER3 and hyperinsulinemic hypoglycemia, familial, 4.