Taking into consideration the above and the urge for better understanding and treatment options for fibrotic lung disease, we sought to determine the expression profiles of EGFR in human disease and correlate our results with expression patterns of known markers of lung fibrosis (type 1 collagen) and functional parameters of disease severity including forced vital capacity (FVC) and diffusion lung capacity for carbon monoxide (DLCO). The gene discussed is EGFR; the disease is pulmonary fibrosis.